Endometrial hyperplasia is an abnormal proliferation, predominantly of the glandular component of the endometrium, which may progress to well differentiated carcinoma in a smal percentage of women. Appropriate management of patients with
endometrial
hyperplasia depends on a number of clinical and pathologic factors. Recently, the International Society of Gynecologic Pathologists, under the auspices of WHO, has developed a novel pathologic classification according to whether cytologic atypia
is
present. However, there have been few clinopathological study of endometrial hyperplasia by this classification.
We have experienced 107 cases with endometrial hyperplasia from January 1988 to December 1993. The age of the study subjects ranged from 27 to 71 years with a mean of 48.7 years. There were 51 cases with simple endometrial hyperplasia, 47 cases
with
complex hyperplasia and 9 cases with atypical endometrial hyperplasia. Pregnancy was never experienced in 9 cases(8.4%) and the mean parity was 2.7. The most frequent complaint was metrorrhagia which was shown in 45 cases(42.1%), whereas
postmenopausal
bleeding in 9 cases(8.4%) and abdominal pain in 4 cases(3.7%) were observed. Out of the 51 cases with simple endometrial hyperplasia, 41 cases were treated by hysterectomy and 2 cases received hormone therapy. From 47 cases with complex
hyperplasia, 42
patients had hysterectomy and only 1 case received hormone therapy. From 9 patients with atypical endometrial hyperplasia, 8 cases underwnet hysterectomy and 1 cases received hormone therapy.
|